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Construction of an Escherichia coli genome with fewer codons sets records – Nature.com

Construction of an Escherichia coli genome with fewer codons sets records – Nature.com

NEWS AND VIEWS 16 May 2019 The biggest synthetic genome so far has been made, with a smaller set of amino-acid-encoding codons than usual — raising the prospect of encoding proteins that contain unnatural amino-acid residues. Over the past decade, decreases in the costs of chemically synthesizing DNA and improved methods for assembling DNA fragments…